Managing chronic knee pain can be overwhelming, especially when exploring treatment options beyond traditional methods like medication or surgery. If you’re suffering from knee osteoarthritis and looking for an innovative, minimally invasive solution, Genicular Artery Embolization (GAE) could be the answer. This cutting-edge procedure has shown promise in alleviating knee pain without the need for major surgery.
At United Knee & Vascular Centers, we understand that making medical decisions requires clarity and confidence. That’s why we’ve compiled the top 10 most frequently asked questions about GAE to help you determine if this procedure is right for you.
1. What is Genicular Artery Embolization (GAE)?
Genicular Artery Embolization (GAE) is a minimally invasive procedure designed to alleviate pain associated with knee osteoarthritis. It involves selectively blocking specific blood vessels—known as genicular arteries—that supply the inflamed areas of the knee. By reducing blood flow to these regions, GAE aims to decrease inflammation and pain, ultimately improving mobility and enhancing overall quality of life.
2. How Does GAE Work?
GAE works by targeting the increased blood supply (hypervascularity) often found in osteoarthritic knees. During the procedure, an interventional radiologist inserts a catheter into the femoral artery and carefully navigates it to the genicular arteries. Tiny embolic particles are then injected through the catheter to partially block blood flow, reducing inflammation and pain in the knee joint.
3. What Are the Benefits of GAE?
GAE offers numerous advantages, making it an attractive option for many individuals dealing with knee osteoarthritis.
Some of the key benefits include:
- No large incisions or lengthy hospital stays.
- Most patients resume light activities within 24 to 48 hours.
- Potential to delay or eliminate knee replacement surgery.
- Low risk of complications compared to surgical alternatives.
- Significant pain relief for many patients, improving their quality of life.
4. Who is a Candidate for GAE?
GAE is best suited for individuals experiencing chronic knee pain due to osteoarthritis who have not found relief through conservative treatments such as physical therapy, medications, or injections. Patients should have a confirmed diagnosis of knee osteoarthritis and undergo a comprehensive evaluation by a healthcare provider to determine eligibility.
5. What Are the Potential Side Effects of GAE?
As with any medical procedure, GAE carries some risks and potential side effects.
Common, temporary side effects include:
- Mild pain or discomfort at the catheter insertion site.
- Bruising or swelling around the treated area.
- Mild fever or fatigue post-procedure.
Severe complications are rare but may include infection, an allergic reaction to contrast material, or unintended embolization of non-target blood vessels. Discussing these risks with your healthcare provider is essential before proceeding with the treatment.
6. What is the Recovery Process Like?
One of the biggest advantages of GAE is the swift recovery time. Most patients are discharged on the same day and can resume light activities within 24 to 48 hours. Full recovery varies but typically occurs within one to two weeks. Your doctor will provide personalized post-procedure care instructions to optimize healing and ensure the best results.
7. How Effective is GAE for Knee Osteoarthritis?
GAE has shown promising results in clinical studies, with many patients experiencing significant pain relief and improved mobility. While individual outcomes may vary, research suggests that GAE provides long-lasting relief for many patients. It is important to have realistic expectations and consult with your healthcare provider about potential outcomes.
8. How Much Does GAE Cost?
The cost of GAE varies based on several factors, including geographic location, healthcare provider fees, and insurance coverage. Some insurance plans may cover the procedure, especially if conservative treatments have failed. Consult your insurance company and healthcare provider to better understand the financial aspects.
9. How Does GAE Compare to Other Treatments for Knee Osteoarthritis?
GAE differs from traditional treatments in several ways:
- Compared to pain medications and injections: These provide temporary relief, while GAE addresses the underlying inflammation.
- Compared to knee replacement surgery: GAE is far less invasive, involves shorter recovery, and carries fewer risks.
- Compared to physical therapy: While physical therapy can be effective, GAE offers a more direct solution for inflammation-related knee pain.
10. How Can I Prepare for GAE?
Preparation for GAE involves a thorough evaluation by an interventional radiologist.
Your pre-procedure assessment may include:
- Imaging studies to assess the severity of knee osteoarthritis.
- Blood tests to ensure overall health and suitability for the procedure.
- A review of your medical history and current medications.
Patients may be advised to fast for a certain period before the procedure and adjust medications as directed by their physician.

Take the Next Step Toward Knee Pain Relief
If chronic knee pain is limiting your mobility and quality of life, Genicular Artery Embolization could be the solution you’ve been searching for.
As a minimally invasive procedure with a quick recovery time and promising results, GAE has become a game-changer for individuals with knee osteoarthritis.
At United Knee & Vascular Centers, our team of specialists is dedicated to providing cutting-edge treatments to help you live pain-free. If you’re interested in learning more about GAE and whether it’s right for you, don’t wait—schedule a consultation today or find a clinic near you to take the first step toward relief!
With GAE, a future with less pain and more mobility is within reach. Let’s work together to get you back to doing what you love!
Frequently Asked Questions
Pain relief from GAE can last anywhere from several months to multiple years, depending on the severity of osteoarthritis and individual response. Some patients experience long-term benefits without needing further treatment.
Studies show that GAE has a success rate of 70–85% in significantly reducing knee pain and improving mobility in patients with osteoarthritis. Results vary based on individual factors and disease progression.
GAE is a minimally invasive alternative to knee replacement that can provide significant pain relief with a shorter recovery time and fewer risks. However, it may not be suitable for severe osteoarthritis cases where joint replacement is the best option. A consultation with a specialist can help determine the right treatment for you.